Tagged questions

How to assign (perturbed) resonances when structure is known?

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I had two problems like this one recently: have protein (in solution) of known general structure resonance assignments...
Posted: Evgeny Fadeev 2571 / Updated: Aleksandr Yakimov 11 Apr 25 at 01:17

Is there a tool to manage NOE and other restraint lists for the structure calculations?

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Hello, I'm currently working on solving a peptide NMR solution structure using NIH-XPLOR. I find myself a lot starting ...
Posted: Evgeny Fadeev 2571 / Updated: Ilango 151 Apr 02 at 05:45

Software to model a 9-mer peptide that binds divalent metals and may oligomerize?

1 1 333
answers votes views
I'm gearing up for a project in which we're looking at the structure of a short peptide that should fold upon binding di...
Posted: jkurutz 71 / Updated: Evgeny Fadeev 2571 Mar 18 at 09:32

How do you use PyMol to visualize structure bundles and related MR data?

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Hello, are you using pymol to analyze NMR structures? (I've been mostly using Molmol before). Have you learned any PyMo...
Updated: Evgeny Fadeev 2571 Mar 02 at 12:29

Are there alternatives to MOLMOL for visualization of NMR structure ensemebles?

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Hi folks, I've been using Molmol, but found significant issues when working with a non-standard structure. For example...
Updated: Evgeny Fadeev 2571 Mar 02 at 08:05

How would you compare solving NMR structure of a smaller peptide vs that of globular protein?

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By smaller peptide I mean somewhere around 15-20 aminoacids, having a cycle or two that constrain the geometry. Also - ...
Updated: Evgeny Fadeev 2571 Feb 27 at 10:23

What are the biggest differences in solving NMR structures of DNA or RNA vs. proteins?

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I've only solved NMR structure of globular proteins (actually in a complex with a short stretch of DNA), but never a str...
Updated: Evgeny Fadeev 2571 Mar 08 at 09:45

How do you find incorrectly assigned NOE restraints?

3 1 651
answers votes views
So you've analyzed your NOE data sets and have 1000+ assigned restraints, with probably inevitable errors. Going through...
Updated: Evgeny Fadeev 2571 Mar 02 at 09:09

How to display NMR structure of molecule with non-standard residues?

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... solving a structure of a cyclic peptide with Ornithine residue, where Orn side-chain participates in an amide bond. ...
Updated: Evgeny Fadeev 2571 Feb 02 at 08:59
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