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Does anybody have any thoughts on this ? I dont really know which is better, CS23D or CS-ROSETTA. Clearly they are identical in terms of I/O..... but Im not sure wether one is considered "superior" to the other .

In summary, my experience with the online servers for these programs is somewhat limited.

asked Jan 05 '11 at 10:20

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I have tried Cs23d before to make a mutated ubiquitin quickly and it worked ok but when I tried with something more challenging it wasn't even close. I haven't tried CS-ROSETTA but from talking to people around conferences it seems better than CS23D. I think CS23D is designed to be simpler to use but the trade off is I don't think it is as good

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answered Jan 05 '11 at 11:50

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Thomas Garner
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How is cs23D easier?

it looks the same to me in terms of data .... (input is a chemical shift list and a fasta file) .

The CS Rosetta website doesnt appear to suggest that any special parameterizations or protocols are required...

I have tried to calculate known structures using both tools and failed, with proteins below 15kD/140 amino acids...

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answered Jan 12 '11 at 07:57

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you don't need to install cs23d its just a web interface - Thomas Garner (Jan 19 '11 at 08:05)

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