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posted Feb 05 '12 at 19:12

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Student Tim
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Isotope Filtered NOESY

I'm an NMR newbie. I know isotope filtering can be used to study a complex under slow exchange, but for fast-exchange, is it possible to acquire only the intramolecular NOEs of the receptor as opposed to intermolecular NOEs between the receptor and ligand? Thanks.

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posted Feb 05 '12 at 19:18

Student%20Tim's gravatar image

Student Tim
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Isotope Filtered NOESY

I'm an NMR newbie. I know isotope filtering can be used to study a complex under slow exchange, but for fast-exchange, is it possible to acquire only the intramolecular NOEs of the receptor as opposed to intermolecular NOEs between the receptor and ligand? I just want the contacts in the receptor. Thanks.

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