I'm an NMR newbie. I know isotope filtering can be used to study a complex under slow exchange, but for fast-exchange, is it possible to acquire only the intramolecular NOEs of the receptor as opposed to intermolecular NOEs between the receptor and ligand? Thanks.

I'm an NMR newbie. I know isotope filtering can be used to study a complex under slow exchange, but for fast-exchange, is it possible to acquire only the intramolecular NOEs of the receptor as opposed to intermolecular NOEs between the receptor and ligand? I just want the contacts in the receptor. Thanks.