Chemical shift

i like this post (click again to cancel)

i dont like this post (click again to cancel)

remove favorite mark from this question (click again to restore mark)

Hi there, I am seeing four signals at equal height between -0.6 and 0.5 PPM of a 1H NMR sample in dmso-d6. The reaction involves a reductive amination of a heterocylic aldehyde and a primary amine with NaCNBH3. Any thoughts.., appreciated.

chemicalshift smallmolecules

asked May 20 '14 at 02:54

TBS
1

One Answer:

oldest newest most voted

1	The BH3 group of cyanoborohydride resonates in this region of the proton spectrum and appears as a 1:1:1:1 quartet to due to 11B coupling. See Li and London, Biotechnology Letters, 28, 623-629, 2002 for a reference. link answered May 23 '14 at 13:02 Eugene DeRose 41

Here (once you log in) you will be able to sign up for the periodic email updates about this question.

Your answer

Please start posting your answer anonymously - your answer will be saved within the current session and published after you log in or create a new account. Please try to give a good answer, for discussions, please use comments and please do remember to vote (login to vote)

toggle preview

Tags:

chemicalshift ×8
smallmolecules ×1

Asked: May 20 '14 at 02:54

Seen: 3,132 times

Last updated: May 23 '14 at 13:02

Related questions