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# Measuring T1 for a low concentration (1mM) compund in water.

Hi,

I'm trying to measure T1 for a compund at 1mM in water using t1ir. Seeing how my concentration is so low, phasing my compund's peaks comes at a great price and so the value of T1 I obtain seems wrong.

I get T1 =1.275s and I calculated my d1= 5xT1 -AQ = 5x1.275 - 5.4525= 0.9225

When I increase the d1 in a watergate 1H acquisition, the intensity of my peeks increases until d1=10s.

Does anyone have an explanation or tips for measuring T1 in water?

# Measuring T1 for a low concentration (1mM) compund compound in water.

Hi,

I'm trying to measure T1 for a compund at 1mM in water using t1ir. Seeing how my concentration is so low, phasing my compund's peaks comes at a great price and so the value of T1 I obtain seems wrong.

I get T1 =1.275s and I calculated my d1= 5xT1 -AQ = 5x1.275 - 5.4525= 0.9225

When I increase the d1 in a watergate 1H acquisition, the intensity of my peeks increases until d1=10s.

Does anyone have an explanation or tips for measuring T1 in water?

# Measuring T1 for a low concentration (1mM) compound in water.

Hi,

I'm trying to measure T1 for a compund at 1mM in water using t1ir. Seeing how my concentration is so low, phasing my compund's compound's peaks comes at a great price and so the value of T1 I obtain seems wrong.

I get T1 =1.275s and I calculated my d1= 5xT1 -AQ = 5x1.275 - 5.4525= 0.9225

When I increase the d1 in a watergate 1H acquisition, the intensity of my peeks increases until d1=10s.

Does anyone have an explanation or tips for measuring T1 in water?