I think that your edasp setup is probably right for 1H observe, with 19F decouple. To check this out, just run 1H with 19F decoupling (parameter set PROF19DEC). If that works, you are O.K.

However, there might be some pulse programming issues for a 1H-19F HOESY (have never actually done one). The 1H amplifier is used for both 1H and 19F, but the QNP switchbox routes the signal to the correct preamp, since 19F is done on the X pre-amp/probe input. You will need some real time switching in the pulse programming to switch the 1H amplifier between the H and X ports. Look at pulse sequence zghfigqn to see how this is done. You can check with Bruker to see if they have a HF HOESY pulse program for a QNP/BBFO type set-up.

I think that your edasp setup is probably right for 1H observe, with 19F decouple. To check this out, just run 1H with 19F decoupling (parameter set PROF19DEC). Just fine a convenient test sample with H-F coupling. If that works, you are O.K.

However, there might be some pulse programming issues for a 1H-19F HOESY (have never actually done one). The 1H amplifier is used for both 1H and 19F, but the QNP switchbox routes the signal to the correct preamp, since 19F is done on the X pre-amp/probe input. You will need some real time switching in the pulse programming to switch the 1H amplifier between the H and X ports. Look at pulse sequence zghfigqn to see how this is done. You can check with Bruker to see if they have a HF HOESY pulse program for a QNP/BBFO type set-up.

I think that your edasp setup is probably right for 1H observe, with 19F decouple. To check this out, just run 1H with 19F decoupling (parameter set PROF19DEC). Just fine a convenient test sample with H-F coupling. If that works, you are O.K.

However, there might be some pulse programming issues for a 1H-19F HOESY (have (I have never actually done one). one myself). The 1H amplifier is used for both 1H and 19F, but the QNP switchbox routes the signal to the correct preamp, since 19F is done on the X pre-amp/probe input. You will need some real time switching in the pulse programming to switch the 1H amplifier between the H and X ports. Look at pulse sequence zghfigqn to see how this is done. You can check with Bruker to see if they have a HF HOESY pulse program for a QNP/BBFO type set-up.

I think that your edasp setup is probably right for 1H observe, with 19F decouple. To check this out, just run 1H with 19F decoupling (parameter set PROF19DEC). PROF19DEC, followed by getprosol). Just fine find a convenient test sample with H-F coupling. If that works, you are O.K.

However, there might be some pulse programming issues for a 1H-19F HOESY (I have never actually done one myself). The 1H amplifier is used for both 1H and 19F, but the QNP switchbox routes the signal to the correct preamp, since 19F is done on the X pre-amp/probe input. You will need some real time switching in the pulse programming to switch the 1H amplifier between the H and X ports. Look at pulse sequence zghfigqn to see how this is done. You can also check with Bruker to see if they have a HF HOESY pulse program for a QNP/BBFO type set-up.

I think that your edasp setup is probably right for 1H observe, with 19F decouple. To check this out, just run 1H with 19F decoupling (parameter set PROF19DEC, followed by getprosol). Just find a convenient test sample with H-F coupling. If that works, you are O.K.

However, there might be some pulse programming issues for a 1H-19F HOESY (I have never actually done one myself). The 1H amplifier is used for both 1H and 19F, but the QNP switchbox routes the signal to the correct preamp, since 19F is done on the X pre-amp/probe input. You will need some real time switching in the pulse programming to switch the 1H amplifier between the H and X ports. Look at pulse sequence zghfigqn to see how this is done. You can also check with Bruker to see if they have a HF HOESY pulse program for a QNP/BBFO type set-up.set-up. You will be using the H/F switch in the QNP box which is a pin-diode device with a response of about 5 us, I think.