Hi! Thomas Garner, I sent a quesry to Prof. Saikia when I read your query to which he kindly sent a reply. I am copying this correspondence for your benefit with the hope that you will find it helpful. [Aravamudhan][1] REPLY from SAIKIA -------------------- **Dear Prof. Aravamudhan, Thank you for your mail which includes information of J- coupling and NOE. Yes, NOE is the best as HMBC not that easy for us. With best regards, Anil K. saikia Professor Department of Chemistry IIT Guwahati Guwahati 781039** ------------------------------- My ([Aravamudhan][2]) message to Saikia: --------------------------------------- *Dear Prof. Saikia, Nice meeting you in Shillong which is our meeting after a long time. I forward this message from my email box received from the nmrwiki. The question on "Correlations across Glycosidic bonds" reminded me of your 4-bond coupling (2 Hz) through an Oxygen atom in your lecture at NEHU recently which required an NOE study for confirmation. This question which you can display by clicking on the hotlink [HERE][3]: [Aravamudhan][4]* [1]: http://ugc-inno-nehu.com/ [2]: http://aravamudhan-s.ucoz.com/ [3]: http://qa.nmrwiki.org/question/243/correlations-across-glycosidic-bonds?sort=latest [4]: http://www.ugc-inno-nehu.com/