Here is a TOCSY recorded with States-TPPI method on a sample in 10/90 D2O/H2O.

States-TPPI is expected to move the "horizontal" solvent artifact to the edges. It does in fact remove most of it, but there is still a considerable residual horizontally running streak.

Are there ways to reduce it by tweaking experimental parameters/pulse sequence?

Thanks!

Here is a TOCSY recorded with States-TPPI method on a sample in 10/90 D2O/H2O.

States-TPPI is expected to move the "horizontal" solvent artifact to the edges. It does in fact remove most of it, but there is still a considerable residual horizontally running streak.

Are there ways to reduce it by tweaking experimental parameters/pulse sequence?

edit: the water suppression scheme is DPFGSE excitation sculpted watergate.

Thanks!