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initial version

posted Sep 27 '11 at 09:16

Kirk%20Marat's gravatar image

Kirk Marat
711

It is certainly possible to observe 19F on most Bruker Avance spectrometers. In many cases, it is as easy as selecting a fluorine parameter set, setting the probe/solvert calibration parameters, and then acquiring the data. A lot will depend on the exact hardware that you have. Probes: The 1H channel on many probes will tune to 19 F. You will have to check yours to be sure. There are dual 1H/19F probes available, and many of the newer brodband probes (BBFO, BBO+ and QNP) will observe 19F through the **X** port on the probe. This enables you to do 1H/19F double resonance. Note that a lot of probes have a 19F background from teflon. Pre-amps. The normal 1H pre-amp isn't typically used for 19F. It is the X pre-amp that will cover 19F (to match with 19F on the X port of the probe). Our system also has a separate 19F pre-amp that we can use for 19F of solids, as it has a 4 kW power limit. Console: The 19F transmit signal is routed through the 1H amplifiers. However, it often then goes through something called a "QNP switchbox" to make sure it is routed to the X port on the probe. On some systems (like our AV 300) it is part of the amplifier, and on others it is a separate unit (like our AV III 500). You can clearly see if this unit is there in the edasp dialog. Filters: You will generally also need some filters if you intend to do 1H/19F double resonance. That's about all I can say without knowing ***exactly*** what hardware you have. If you send me some details, I can give you some more tips. On our systems (AV 300 with QNP probe and AV III 500 with BBFO ATM probe), running 19F with or without 1H decoupling and 1H with 19F decoupling is as simple as running normal proton and carbon spectra. A lot just depends on making sure that the software, cabling and calibration files have been properly configured. Bruker probably did this at installation. Cheers -Kirk
click to hide/show revision 2
No.1 Revision

posted Sep 27 '11 at 09:18

Kirk%20Marat's gravatar image

Kirk Marat
711

It is certainly possible to observe 19F on most Bruker Avance spectrometers. In many cases, it is as easy as selecting a fluorine parameter set, setting the probe/solvert calibration parameters, and then acquiring the data. A lot will depend on the exact hardware that you have.

Probes: The 1H channel on many probes will tune to 19 F. You will have to check yours to be sure. There are dual 1H/19F probes available, and many of the newer brodband probes (BBFO, BBO+ and QNP) will observe 19F through the X port on the probe. This enables you to do 1H/19F double resonance. Note that a lot of probes have a 19F background from teflon.

Pre-amps. The normal 1H pre-amp isn't typically used for 19F. It is the X pre-amp that will cover 19F (to match with 19F on the X port of the probe). Our system also has a separate 19F pre-amp that we can use for 19F of solids, as it has a 4 kW power limit.

Console: The 19F transmit signal is routed through the 1H amplifiers. However, it often then goes through something called a "QNP switchbox" to make sure it is routed to the X port on the probe. On some systems (like our AV 300) it is part of the amplifier, and on others it is a separate unit (like our AV III 500). You can clearly see if this unit is there in the edasp dialog.

Filters: You will generally also need some filters if you intend to do 1H/19F double resonance.

That's about all I can say without knowing exactly what hardware you have. If you send me some details, I can give you some more tips.

On our systems (AV 300 with QNP probe and AV III 500 with BBFO ATM probe), running 19F with or without 1H decoupling and 1H with 19F decoupling is as simple as running normal proton and carbon spectra. A lot just depends on making sure that the software, cabling and calibration files have been properly configured. Bruker probably did this at installation.

Cheers -Kirk

click to hide/show revision 3
No.2 Revision

posted Sep 27 '11 at 09:19

Kirk%20Marat's gravatar image

Kirk Marat
711

It is certainly possible to observe 19F on most Bruker Avance spectrometers. In many cases, it is as easy as selecting a fluorine parameter set, setting the probe/solvert calibration parameters, and then acquiring the data. A lot will depend on the exact hardware that you have.

Probes: The 1H channel on many probes will tune to 19 F. You will have to check yours to be sure. There are dual 1H/19F probes available, and many of the newer brodband probes (BBFO, BBO+ and QNP) will observe 19F through the X port on the probe. This enables you to do 1H/19F double resonance. Note that a lot of probes have a 19F background from teflon.

Pre-amps. The normal 1H pre-amp isn't typically used for 19F. It is the X pre-amp that will cover 19F (to match with 19F on the X port of the probe). Our system also has a separate 19F pre-amp that we can use for 19F of solids, as it has a 4 kW power limit.

Console: The 19F transmit signal is routed through the 1H amplifiers. However, it often then goes through something called a "QNP switchbox" to make sure it is routed to the X port on the probe. On some systems (like our AV 300) it is part of the amplifier, and on others it is a separate unit (like our AV III 500). You can clearly see if this unit is there in the edasp dialog.

Filters: You will also need some filters if you intend to do 1H/19F double resonance.

That's about all I can say without knowing exactly what hardware you have. If you send me some details, I can give you some more tips.

On our systems (AV 300 with QNP probe and AV III 500 with BBFO ATM probe), running 19F with or without 1H decoupling decoupling, and 1H with 19F decoupling decoupling, is as simple as running normal proton and carbon spectra. A lot just depends on making sure that the software, cabling and calibration files have been properly configured. Bruker probably did this at installation.

Cheers -Kirk

click to hide/show revision 4
No.3 Revision

posted Sep 27 '11 at 10:27

Kirk%20Marat's gravatar image

Kirk Marat
711

It is certainly possible to observe 19F on most Bruker Avance spectrometers. In many cases, it is as easy as selecting a fluorine parameter set, setting the probe/solvert calibration parameters, and then acquiring the data. A lot will depend on the exact hardware that you have.

Probes: The 1H channel on many probes will tune to 19 F. You will have to check yours to be sure. There are dual 1H/19F probes available, and many of the newer brodband probes (BBFO, BBO+ and QNP) will observe 19F through the X port on the probe. This enables you to do 1H/19F double resonance. Note that a lot of probes have a 19F background from teflon.

Pre-amps. The normal 1H pre-amp isn't typically used for 19F. It is the X pre-amp that will cover 19F (to match with 19F on the X port of the probe). Our system also has a separate 19F pre-amp that we can use for 19F of solids, as it has a 4 kW power limit.

Console: The 19F transmit signal is routed through the 1H amplifiers. However, it often then goes through something called a "QNP switchbox" to make sure it is routed to the X port on the probe. On some systems (like our AV 300) it is part of the amplifier, and on others it is a separate unit (like our AV III 500). You can clearly see if this unit is there in the edasp dialog.dialog. If you don't have this unit, then you will have to do a bit of recabling to accomplish the same thing.

Filters: You will also need some filters if you intend to do 1H/19F double resonance.

That's about all I can say without knowing exactly what hardware you have. If you send me some details, I can give you some more tips.

On our systems (AV 300 with QNP probe and AV III 500 with BBFO ATM probe), running 19F with or without 1H decoupling, and 1H with 19F decoupling, is as simple as running normal proton and carbon spectra. A lot just depends on making sure that the software, cabling and calibration files have been properly configured. Bruker probably did this at installation.

Cheers -Kirk

click to hide/show revision 5
No.4 Revision

posted Sep 27 '11 at 10:28

Kirk%20Marat's gravatar image

Kirk Marat
711

It is certainly possible to observe 19F on most Bruker Avance spectrometers. In many cases, it is as easy as selecting a fluorine parameter set, setting the probe/solvert calibration parameters, and then acquiring the data. A lot will depend on the exact hardware that you have.

Probes: Probes: The 1H channel on many probes will tune to 19 F. You will have to check yours to be sure. There are dual 1H/19F probes available, and many of the newer brodband probes (BBFO, BBO+ and QNP) will observe 19F through the X port on the probe. This enables you to do 1H/19F double resonance. Note that a lot of probes have a 19F background from teflon.

Pre-amps. Pre-amps: The normal 1H pre-amp isn't typically used for 19F. It is the X pre-amp that will cover 19F (to match with 19F on the X port of the probe). Our system also has a separate 19F pre-amp that we can use for 19F of solids, as it has a 4 kW power limit.

Console: Console: The 19F transmit signal is routed through the 1H amplifiers. However, it often then goes through something called a "QNP switchbox" to make sure it is routed to the X port on the probe. On some systems (like our AV 300) it is part of the amplifier, and on others it is a separate unit (like our AV III 500). You can clearly see if this unit is there in the edasp dialog. If you don't have this unit, then you will have to do a bit of recabling to accomplish the same thing.

Filters: Filters: You will also need some filters if you intend to do 1H/19F double resonance.

That's about all I can say without knowing exactly what hardware you have. If you send me some details, I can give you some more tips.

On our systems (AV 300 with QNP probe and AV III 500 with BBFO ATM probe), running 19F with or without 1H decoupling, and 1H with 19F decoupling, is as simple as running normal proton and carbon spectra. A lot just depends on making sure that the software, cabling and calibration files have been properly configured. Bruker probably did this at installation.

Cheers -Kirk

click to hide/show revision 6
No.5 Revision

posted Sep 27 '11 at 10:40

Kirk%20Marat's gravatar image

Kirk Marat
711

It is certainly possible to observe 19F on most Bruker Avance spectrometers. In many cases, it is as easy as selecting a fluorine parameter set, setting the probe/solvert calibration parameters, and then acquiring the data. A lot will depend on the exact hardware that you have.

Probes: The 1H channel on many probes will tune to 19 F. You will have to check yours to be sure. There are dual 1H/19F probes available, and many of the newer brodband probes (BBFO, BBO+ and QNP) will observe 19F through the X port on the probe. This enables you to do 1H/19F double resonance. Note that a lot of probes have a 19F background from teflon.

Pre-amps: The normal 1H pre-amp isn't typically used for 19F. It is the X pre-amp that will cover 19F (to match with 19F on the X port of the probe). Check that your X pre-amp covers 19F. The sticker on the back of the pre-amp will tell you. It will say something like XBB19F. Our system also has a separate 19F pre-amp that we can use for 19F of solids, as it has a 4 kW power limit.

Console: The 19F transmit signal is routed through the 1H amplifiers. However, it often then goes through something called a "QNP switchbox" to make sure it is routed to the X port on the probe. On some systems (like our AV 300) it is part of the amplifier, and on others it is a separate unit (like our AV III 500). You can clearly see if this unit is there in the edasp dialog. If you don't have this unit, then you will have to do a bit of recabling to accomplish the same thing.

Filters: You will also need some filters if you intend to do 1H/19F double resonance.

That's about all I can say without knowing exactly what hardware you have. If you send me some details, I can give you some more tips.

On our systems (AV 300 with QNP probe and AV III 500 with BBFO ATM probe), running 19F with or without 1H decoupling, and 1H with 19F decoupling, is as simple as running normal proton and carbon spectra. A lot just depends on making sure that the software, cabling and calibration files have been properly configured. Bruker probably did this at installation.

Cheers -Kirk

click to hide/show revision 7
No.6 Revision

posted Sep 27 '11 at 10:40

Kirk%20Marat's gravatar image

Kirk Marat
711

It is certainly possible to observe 19F on most Bruker Avance spectrometers. In many cases, it is as easy as selecting a fluorine parameter set, setting the probe/solvert calibration parameters, and then acquiring the data. A lot will depend on the exact hardware that you have.

Probes: The 1H channel on many probes will tune to 19 F. You will have to check yours to be sure. There are dual 1H/19F probes available, and many of the newer brodband probes (BBFO, BBO+ and QNP) will observe 19F through the X port on the probe. This enables you to do 1H/19F double resonance. Note that a lot of probes have a 19F background from teflon.

Pre-amps: The normal 1H pre-amp isn't typically used for 19F. It is the X pre-amp that will cover 19F (to match with 19F on the X port of the probe). Check that your X pre-amp covers 19F. The sticker on the back of the pre-amp will tell you. It will say something like XBB19F. Our system also has a separate 19F pre-amp that we can use for 19F of solids, as it has a 4 kW power limit.limit. It can also be used for liquids if we want.

Console: The 19F transmit signal is routed through the 1H amplifiers. However, it often then goes through something called a "QNP switchbox" to make sure it is routed to the X port on the probe. On some systems (like our AV 300) it is part of the amplifier, and on others it is a separate unit (like our AV III 500). You can clearly see if this unit is there in the edasp dialog. If you don't have this unit, then you will have to do a bit of recabling to accomplish the same thing.

Filters: You will also need some filters if you intend to do 1H/19F double resonance.

That's about all I can say without knowing exactly what hardware you have. If you send me some details, I can give you some more tips.

On our systems (AV 300 with QNP probe and AV III 500 with BBFO ATM probe), running 19F with or without 1H decoupling, and 1H with 19F decoupling, is as simple as running normal proton and carbon spectra. A lot just depends on making sure that the software, cabling and calibration files have been properly configured. Bruker probably did this at installation.

Cheers -Kirk

click to hide/show revision 8
No.7 Revision

posted Sep 27 '11 at 12:14

Kirk%20Marat's gravatar image

Kirk Marat
711

It is certainly possible to observe 19F on most Bruker Avance spectrometers. In many cases, it is as easy as selecting a fluorine parameter set, setting the probe/solvert calibration parameters, and then acquiring the data. A lot will depend on the exact hardware that you have.

Probes: The 1H channel on many probes will tune to 19 F. You will have to check yours to be sure. There are dual 1H/19F probes available, and many of the newer brodband broadband probes (BBFO, BBO+ and QNP) will observe 19F through the X port on the probe. This enables you to do 1H/19F double resonance. Note that a lot of probes have a 19F background from teflon.

Pre-amps: The normal 1H pre-amp isn't typically used for 19F. It is the X pre-amp that will cover 19F (to match with 19F on the X port of the probe). Check that your X pre-amp covers 19F. The sticker on the back of the pre-amp will tell you. It will say something like XBB19F. Our system also has a separate 19F pre-amp that we can use for 19F of solids, as it has a 4 kW power limit. It can also be used for liquids if we want.

Console: The 19F transmit signal is routed through the 1H amplifiers. However, it often then goes through something called a "QNP switchbox" to make sure it is routed to the X port on the probe. On some systems (like our AV 300) it is part of the amplifier, and on others it is a separate unit (like our AV III 500). You can clearly see if this unit is there in the edasp dialog. If you don't have this unit, then you will have to do a bit of recabling to accomplish the same thing.

Filters: You will also need some filters if you intend to do 1H/19F double resonance.

That's about all I can say without knowing exactly what hardware you have. If you send me some details, I can give you some more tips.

On our systems (AV 300 with QNP probe and AV III 500 with BBFO ATM probe), running 19F with or without 1H decoupling, and 1H with 19F decoupling, is as simple as running normal proton and carbon spectra. A lot just depends on making sure that the software, cabling and calibration files have been properly configured. Bruker probably did this at installation.

Cheers -Kirk

click to hide/show revision 9
No.8 Revision

posted Sep 27 '11 at 12:16

Kirk%20Marat's gravatar image

Kirk Marat
711

It is certainly possible to observe 19F on most Bruker Avance spectrometers. In many cases, it is as easy as selecting a fluorine parameter set, setting the probe/solvert calibration parameters, and then acquiring the data. A lot will depend on the exact hardware that you have.

Probes: The 1H channel on many probes will tune to 19 F. You will have to check yours to be sure. There are dual 1H/19F probes available, and many of the newer broadband probes (BBFO, BBO+ and QNP) will observe 19F through the X port on the probe. This enables you to do 1H/19F double resonance. Note that a lot of probes have a 19F background from teflon.

Pre-amps: The normal 1H pre-amp isn't typically used for 19F. It is the X pre-amp that will cover 19F (to match with 19F on the X port of the probe). Check that your X pre-amp covers 19F. The sticker on the back of the pre-amp will tell you. It will say something like XBB19F. Our system also has a separate 19F pre-amp that we can use for 19F of solids, as it has a 4 kW power limit. It can also be used for liquids if we want.

Console: The 19F transmit signal is routed through the 1H amplifiers. However, it often then goes through something called a "QNP switchbox" to make sure it is the RF is automatically routed to the X port on the probe. On some systems (like our AV 300) 300), it is part of the amplifier, and on others it is a separate unit (like our AV III 500). You can clearly see if this unit is there in the edasp dialog. If you don't have this unit, then you will have to do a bit of recabling to accomplish the same thing.

Filters: You will also need some filters if you intend to do 1H/19F double resonance.

That's about all I can say without knowing exactly what hardware you have. If you send me some details, I can give you some more tips.

On our systems (AV 300 with QNP probe and AV III 500 with BBFO ATM probe), running 19F with or without 1H decoupling, and 1H with 19F decoupling, is as simple as running normal proton and carbon spectra. A lot just depends on making sure that the software, cabling and calibration files have been properly configured. Bruker probably did this at installation.

Cheers -Kirk

click to hide/show revision 10
No.9 Revision

posted Sep 27 '11 at 12:34

Kirk%20Marat's gravatar image

Kirk Marat
711

It is certainly possible to observe 19F on most Bruker Avance spectrometers. In many cases, it is as easy as selecting a fluorine parameter set, setting the probe/solvert probe/solvent calibration parameters, and then acquiring the data. A lot will depend on the exact hardware that you have.

Probes: The 1H channel on many probes will tune to 19 F. You will have to check yours to be sure. There are dual 1H/19F probes available, and many of the newer broadband probes (BBFO, BBO+ and QNP) will observe 19F through the X port on the probe. This enables you to do 1H/19F double resonance. Note that a lot of probes have a 19F background from teflon.

Pre-amps: The normal 1H pre-amp isn't typically used for 19F. It is the X pre-amp that will cover 19F (to match with 19F on the X port of the probe). Check that your X pre-amp covers 19F. The sticker on the back of the pre-amp will tell you. It will say something like XBB19F. Our system also has a separate 19F pre-amp that we can use for 19F of solids, as it has a 4 kW power limit. It can also be used for liquids if we want.

Console: The 19F transmit signal is routed through the 1H amplifiers. However, it often then goes through something called a "QNP switchbox" to make sure the RF is automatically routed to the X port on the probe. On some systems (like our AV 300), it is part of the amplifier, and on others it is a separate unit (like our AV III 500). You can clearly see if this unit is there in the edasp dialog. If you don't have this unit, then you will have to do a bit of recabling to accomplish the same thing.

Filters: You will also need some filters if you intend to do 1H/19F double resonance.

That's about all I can say without knowing exactly what hardware you have. If you send me some details, I can give you some more tips.

On our systems (AV 300 with QNP probe and AV III 500 with BBFO ATM probe), running 19F with or without 1H decoupling, and 1H with 19F decoupling, is as simple as running normal proton and carbon spectra. A lot just depends on making sure that the software, cabling and calibration files have been properly configured. Bruker probably did this at installation.

Cheers -Kirk

click to hide/show revision 11
No.10 Revision

posted Sep 27 '11 at 16:35

Kirk%20Marat's gravatar image

Kirk Marat
711

It is certainly possible to observe 19F on most Bruker Avance spectrometers. In many cases, it is as easy as selecting a fluorine parameter set, setting the probe/solvent calibration parameters, and then acquiring the data. A lot will depend on the exact hardware that you have.

Probes: The 1H channel on many probes will tune to 19 F. You will have to check yours to be sure. There are dual 1H/19F probes available, and many of the newer broadband probes (BBFO, BBO+ and QNP) will observe 19F through the X port on the probe. This enables you to do 1H/19F double resonance. These probes will be identified in the label.

To check whether the proton channel of a regular BBO probe will tune to fluorine, the best tool is a network analyzer. If you don't have acces to one, you can use the software tuning program 'wobb'. This requires that the console be properly set-up for fluorine.

Note that a lot of probes have a 19F background from teflon.

Pre-amps: The normal 1H pre-amp isn't typically used for 19F. It is the X pre-amp that will cover 19F (to match with 19F on the X port of the probe). Check that your X pre-amp covers 19F. The sticker on the back of the pre-amp will tell you. It will say something like XBB19F. Our system also has a separate 19F pre-amp that we can use for 19F of solids, as it has a 4 kW power limit. It can also be used for liquids if we want.

Console: The 19F transmit signal is routed through the 1H amplifiers. However, it often then goes through something called a "QNP switchbox" to make sure the RF is automatically routed to the X port on the probe. On some systems (like our AV 300), it is part of the amplifier, and on others it is a separate unit (like our AV III 500). You can clearly see if this unit is there in the edasp dialog. If you don't have this unit, then you will have to do a bit of recabling to accomplish the same thing.

Filters: You will also need some filters if you intend to do 1H/19F double resonance.

That's about all I can say without knowing exactly what hardware you have. If you send me some details, I can give you some more tips.

On our systems (AV 300 with QNP probe and AV III 500 with BBFO ATM probe), running 19F with or without 1H decoupling, and 1H with 19F decoupling, is as simple as running normal proton and carbon spectra. A lot just depends on making sure that the software, cabling and calibration files have been properly configured. Bruker probably did this at installation.

Cheers -Kirk

click to hide/show revision 12
No.11 Revision

posted Sep 27 '11 at 16:36

Kirk%20Marat's gravatar image

Kirk Marat
711

It is certainly possible to observe 19F on most Bruker Avance spectrometers. In many cases, it is as easy as selecting a fluorine parameter set, setting the probe/solvent calibration parameters, and then acquiring the data. A lot will depend on the exact hardware that you have.

Probes: The 1H channel on many probes will tune to 19 F. You will have to check yours to be sure. There are dual 1H/19F probes available, and many of the newer broadband probes (BBFO, BBO+ and QNP) will observe 19F through the X port on the probe. This enables you to do 1H/19F double resonance. These probes will be clearly identified in on the label.

To check whether the proton channel of a regular BBO probe will tune to fluorine, the best tool is a network analyzer. If you don't have acces to one, you can use the software tuning program 'wobb'. This requires that the console be properly set-up for fluorine.

Note that a lot of probes have a 19F background from teflon.

Pre-amps: The normal 1H pre-amp isn't typically used for 19F. It is the X pre-amp that will cover 19F (to match with 19F on the X port of the probe). Check that your X pre-amp covers 19F. The sticker on the back of the pre-amp will tell you. It will say something like XBB19F. Our system also has a separate 19F pre-amp that we can use for 19F of solids, as it has a 4 kW power limit. It can also be used for liquids if we want.

Console: The 19F transmit signal is routed through the 1H amplifiers. However, it often then goes through something called a "QNP switchbox" to make sure the RF is automatically routed to the X port on the probe. On some systems (like our AV 300), it is part of the amplifier, and on others it is a separate unit (like our AV III 500). You can clearly see if this unit is there in the edasp dialog. If you don't have this unit, then you will have to do a bit of recabling to accomplish the same thing.

Filters: You will also need some filters if you intend to do 1H/19F double resonance.

That's about all I can say without knowing exactly what hardware you have. If you send me some details, I can give you some more tips.

On our systems (AV 300 with QNP probe and AV III 500 with BBFO ATM probe), running 19F with or without 1H decoupling, and 1H with 19F decoupling, is as simple as running normal proton and carbon spectra. A lot just depends on making sure that the software, cabling and calibration files have been properly configured. Bruker probably did this at installation.

Cheers -Kirk

click to hide/show revision 13
No.12 Revision

posted Sep 28 '11 at 12:34

Kirk%20Marat's gravatar image

Kirk Marat
711

It is certainly possible to observe 19F on most Bruker Avance spectrometers. In many cases, it is as easy as selecting a fluorine parameter set, setting the probe/solvent calibration parameters, and then acquiring the data. A lot will depend on the exact hardware that you have.

Probes: The 1H channel on many probes will tune to 19 F. You will have to check yours to be sure. There are dual 1H/19F probes available, and many of the newer broadband probes (BBFO, BBO+ and QNP) will observe 19F through the X port on the probe. This enables you to do 1H/19F double resonance. These probes will be clearly identified on the label.

To check whether the proton channel of a regular BBO probe will tune to fluorine, the best tool is a network analyzer. If you don't have acces access to one, you can use the software tuning program 'wobb'. This requires that the console be properly set-up for fluorine.

Note that a lot of probes have a 19F background from teflon.

Pre-amps: The normal 1H pre-amp isn't typically used for 19F. It is the X pre-amp that will cover 19F (to match with 19F on the X port of the probe). Check that your X pre-amp covers 19F. The sticker on the back of the pre-amp will tell you. It will say something like XBB19F. Our system also has a separate 19F pre-amp that we can use for 19F of solids, as it has a 4 kW power limit. It can also be used for liquids if we want.

Console: The 19F transmit signal is routed through the 1H amplifiers. However, it often then goes through something called a "QNP switchbox" to make sure the RF is automatically routed to the X port on the probe. On some systems (like our AV 300), it is part of the amplifier, and on others it is a separate unit (like our AV III 500). You can clearly see if this unit is there in the edasp dialog. If you don't have this unit, then you will have to do a bit of recabling to accomplish the same thing.

Filters: You will also need some filters if you intend to do 1H/19F double resonance.

That's about all I can say without knowing exactly what hardware you have. If you send me some details, I can give you some more tips.

On our systems (AV 300 with QNP probe and AV III 500 with BBFO ATM probe), running 19F with or without 1H decoupling, and 1H with 19F decoupling, is as simple as running normal proton and carbon spectra. A lot just depends on making sure that the software, cabling and calibration files have been properly configured. Bruker probably did this at installation.

Cheers -Kirk

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